Because there is generally some level of sympathetic tone on the heart beta-blockers are able to reduce sympathetic influences that normally stimulate chronotropy heart rate inotropy contractility dromotropy electrical conduction and lusitropy relaxation. Beta-blockers are indicated and have FDA approval for the treatment of tachycardia hypertension myocardial infarction congestive heart failure cardiac arrhythmias coronary artery disease hyperthyroidism essential tremor aortic dissection.
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Beta-blockers as a class of drugs are primarily used to treat cardiovascular diseases and other conditions.
. Therefore beta-blockers cause decreases in heart rate contractility conduction velocity and relaxation rate.
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